The National Institute on Aging has announced its intent to commit $2.8 million to research of cognition among Alzheimer's disease patients.
Dr. Paul Crane, a UW Medicine neuroscientist and professor of medicine at the University of Washington, is principal investigator of the multi-institution project. It is now funded for five more years to develop statistical approaches to scoring patients' cognitive abilities.
“Our group has been at the forefront of using modern statistical and psychometric methods to optimize scores for cognitive functioning in Alzheimer’s research,” said Crane, who is also an attending physician at Harborview Medical Center. “Our work in the previous cycle focused on memory and executive functioning. This cycle, we will extend that work to consider other cognitive domains. We proposed to use optimized cognitive measures to further our scientific understanding of the earliest changes on the road towards Alzheimer’s disease, and to further our understanding of variation in cognitive function among people who have Alzheimer’s disease.”
Colleagues on the grant represent Brown University, Indiana University, the University of California at Davis, Johns Hopkins University, VU University Medical Center in Amsterdam, Boston University, and Rush University Medical Center.